TY - JOUR
T1 - Water-soluble Re
6
-clusters with aromatic phosphine ligands-from synthesis to potential biomedical applications
AU - Ivanov, Anton A.
AU - Konovalov, Dmitry I.
AU - Pozmogova, Tatiana N.
AU - Solovieva, Anastasiya O.
AU - Melnikov, Anatoly R.
AU - Brylev, Konstantin A.
AU - Kuratieva, Natalia V.
AU - Yanshole, Vadim V.
AU - Kirakci, Kaplan
AU - Lang, Kamil
AU - Cheltygmasheva, Svetlana N.
AU - Kitamura, Noboru
AU - Shestopalova, Lidiya V.
AU - Mironov, Yuri V.
AU - Shestopalov, Michael A.
PY - 2019/4/1
Y1 - 2019/4/1
N2 -
The development of water-soluble hexanuclear cluster complexes of low toxicity is a promising task due to their potential biomedical applications such as bioimaging and photodynamic therapy. Herein, we present the syntheses of two new water-soluble hexarhenium cluster complexes with terminal amphiphilic phosphine ligands, and delineate their photoluminescence and X-ray excited optical luminescence (XEOL) properties. These cluster complexes, namely [{Re
6
Q
8
}(PPh
2
CH
2
CH
2
COO)
6
]
4-
(Q = S (1); Se, (2)), have the least cytotoxicity among all the tested hexanuclear metal-clusters, are capable of penetrating into cells and exhibit moderate photodynamic toxicity toward Hep-2 cells.
AB -
The development of water-soluble hexanuclear cluster complexes of low toxicity is a promising task due to their potential biomedical applications such as bioimaging and photodynamic therapy. Herein, we present the syntheses of two new water-soluble hexarhenium cluster complexes with terminal amphiphilic phosphine ligands, and delineate their photoluminescence and X-ray excited optical luminescence (XEOL) properties. These cluster complexes, namely [{Re
6
Q
8
}(PPh
2
CH
2
CH
2
COO)
6
]
4-
(Q = S (1); Se, (2)), have the least cytotoxicity among all the tested hexanuclear metal-clusters, are capable of penetrating into cells and exhibit moderate photodynamic toxicity toward Hep-2 cells.
UR - http://www.scopus.com/inward/record.url?scp=85063429787&partnerID=8YFLogxK
U2 - 10.1039/c8qi01216d
DO - 10.1039/c8qi01216d
M3 - Article
AN - SCOPUS:85063429787
VL - 6
SP - 882
EP - 892
JO - Inorganic Chemistry Frontiers
JF - Inorganic Chemistry Frontiers
SN - 2052-1545
IS - 4
ER -