Volatile and Intravenous Anesthetics for Brain Protection in Cardiac Surgery: Does the Choice of Anesthesia Matter?

Vladimir V. Lomivorotov, Gleb Moroz, Marat Abubakirov, Roman Osinsky, Giovanni Landoni

Результат исследования: Научные публикации в периодических изданияхобзорная статьярецензирование

Аннотация

Postoperative neurologic complications have a significant effect on morbidity, mortality, and long-term disability in patients undergoing cardiac surgery. The etiology of brain injury in patients undergoing cardiac surgery is multifactorial and remains unclear. There are several perioperative causative factors for neurologic complications, including microembolization, hypoperfusion, and systemic inflammatory response syndrome. Despite technologic advances and the development of new anesthetic drugs, there remains a high rate of postoperative neurologic complications. Moreover, despite the strong evidence that volatile anesthesia exerts cardioprotective effects in patients undergoing cardiac surgery, the neuroprotective effects of volatile agents remain unclear. Several studies have reported an association of using volatile anesthetics with improvement of biochemical markers of brain injury and postoperative neurocognitive function. However, there is a need for additional studies to define the optimal anesthetic drug for protecting the brain in patients undergoing cardiac surgery.

Язык оригиналаанглийский
ЖурналJournal of Cardiothoracic and Vascular Anesthesia
Ранняя дата в режиме онлайн22 фев 2021
DOI
СостояниеЭлектронная публикация перед печатью - 22 фев 2021

Предметные области OECD FOS+WOS

  • 3.02 КЛИНИЧЕСКАЯ МЕДИЦИНА
  • 3.02.DQ СЕРДЕЧНАЯ И СЕРДЕЧНО-СОСУДИСТАЯ СИСТЕМЫ
  • 3.02.BA АНЕСТЕЗИОЛОГИЯ

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