Dyshidrotic dermatitis (pompholyx) is a chronic and/or recurrent vesicular eczema of the palmar sides of the hands and sometimes the soles of the feet. The major aetiologies to be considered are atopic dyshidrotic eczema, contact dyshidrotic eczema and systemic contact dyshidrotic eczema. The aim of the study was to determine the nature of specific hypersensitivity in patients with pompholyx. Material and methods. The observation involved 75 patients aged between 18 and 45 years. The level and spectrum of sensitization was defined in patients with pompholyx, atopic dermatitis and people that aren’t burdened with individual and family atopic anamnesis. 1500 allergy tests were conducted generally. Results. The level of total IgE was elevated in 27,2 % patients with pompholyx and in 52,4 % patients with atopic dermatitis (p> 0,05). Frequency of specific sensitization in patients with pompholyx is comparable to a control group – 40 %, in a contrast to patients with atopic dermatitis – 76 % (p< 0,01). Conclusion. There are no significant differences in the spectrum of specific sensitization in patients with pompholyx and the control group (p>0,05). Patients with pompholyx prevailed sensitization to house dust mite – 24 %. In group with pompholyx sensitization to pets epithelium were absent, in contrast to patients with atopic dermatitis (p< 0,001).
|Журнал||International Review of Allergology and Clinical Immunology in Family Medicine|
|Состояние||Опубликовано - 1 янв 2017|