Theoretical Substantiation for the Original Technique of Photodynamic Fractional Laser Photothermolysis (PFLP) for Dermatology, based on Intradermal Transport of Photosensibilisers

Sergey Nikonov, Danila Chernopyatov, Oleg Shumkov, Mikhail Soluyanov, Mikhail Smagin

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференцийстатья в сборнике материалов конференциинаучнаярецензирование

Аннотация

This review demonstrates the progress, current status and problems of photodynamic therapy and laser photothermolysis for various skin diseases and rejuvenation. These new minimally invasive technologies are detailed from the points of view of their advantages and disadvantages. Particular attention is paid to complications, associated with prolonged dermal phototoxicity after intravenous photosensibilisation and insufficient intradermal penetration of photosensibilisers after local application to skin. Finding a compromise between phototoxicity and insufficiency of local photosensibilisation we've developed a technical approach employed to overcome limitations associated with targeted delivery of photosensibilisers into deep dermal layers. Intradermal delivery of photosensibilisers through so-called microthermal zones or dermal micropores, formed by focused pulse-periodic radiation of fiber laser, previously never used for photodynamic therapy of dermal disorders.

Язык оригиналаанглийский
Название основной публикацииSIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings
ИздательInstitute of Electrical and Electronics Engineers Inc.
Страницы1007-1010
Число страниц4
ISBN (электронное издание)9781728144016
DOI
СостояниеОпубликовано - окт 2019
Событие2019 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2019 - Novosibirsk, Российская Федерация
Продолжительность: 21 окт 201927 окт 2019

Серия публикаций

НазваниеSIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings

Конференция

Конференция2019 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2019
СтранаРоссийская Федерация
ГородNovosibirsk
Период21.10.201927.10.2019

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    Nikonov, S., Chernopyatov, D., Shumkov, O., Soluyanov, M., & Smagin, M. (2019). Theoretical Substantiation for the Original Technique of Photodynamic Fractional Laser Photothermolysis (PFLP) for Dermatology, based on Intradermal Transport of Photosensibilisers. В SIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings (стр. 1007-1010). [8958204] (SIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SIBIRCON48586.2019.8958204