The tendency to hypercoagulation in the perioperative period of uterine artery embolization

Siutkina Irina, Khabarov Dmitriy, Smagin Alexandr, Bulychev Pavel, Demura Alexander, Inyoshina Alisa

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференцийстатья в сборнике материалов конференциинаучнаярецензирование

Аннотация

Purpose of the study: to assess the dynamics of changes in the blood coagulation system in the perioperative period during uterine artery embolization (UAE) based on monitoring of hemostasis system's indicators, including TEG, and the tendency (or its absence) to thrombosis. The study included 37 patients with EMA, who in the course of preoperative examination excluded the contributing risk factors for thromboembolic complications. In the perioperative period, dynamic monitoring of coagulogram and thromboelastography was performed. One day after the UAE, the patients showed a tendency to hypercoagulation according to the TEG data (a decrease in the R, K time indices and an increase in the a-angle, MA value) and fibrinolysis activation (increased LY 30 index). At the same time, in the study of coagulogram indices, an increased level of hypercoagulation markers (fibrinogen, D-dimer, SFMC), Prothrombin index and a decreased APTT were revealed. Findings indicate, in general, an increased risk of VTE complications in the postoperative period after UAE. The revealed features of changes in hemostasis parameters in patients after UAE indicate the need for continuous monitoring of the hemostasis system and the development of effective measures for the prevention of VTE complication.

Язык оригиналаанглийский
Название основной публикацииProceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
ИздательInstitute of Electrical and Electronics Engineers Inc.
Страницы265-268
Число страниц4
ISBN (электронное издание)9781728195971
DOI
СостояниеОпубликовано - июл 2020
Событие2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020 - Novosibirsk, Российская Федерация
Продолжительность: 6 июл 202010 июл 2020

Серия публикаций

НазваниеProceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020

Конференция

Конференция2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
СтранаРоссийская Федерация
ГородNovosibirsk
Период06.07.202010.07.2020

Предметные области OECD FOS+WOS

  • 1.02 КОМПЬЮТЕРНЫЕ И ИНФОРМАЦИОННЫЕ НАУКИ
  • 1.06 БИОЛОГИЧЕСКИЕ НАУКИ
  • 3.01 ФУНДАМЕНТАЛЬНАЯ МЕДИЦИНА
  • 3.03 НАУКИ О ЗДОРОВЬЕ
  • 5.09 ПРОЧИЕ СОЦИАЛЬНЫЕ НАУКИ

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