The characterization of exosomes from biological fluids of patients with different types of cancer

N. V. Yunusova, S. N. Tamkovich, M. N. Stakheeva, A. A. Grigor'Eva, A. K. Somov, E. A. Tugutova, L. A. Kolomiets, S. V. Molchanov, S. G. Afanas'Ev, G. V. Kakurina, E. L. Choinzonov, I. V. Kondakova

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференцийстатья в сборнике материалов конференциинаучнаярецензирование

5 Цитирования (Scopus)

Аннотация

Exosomes are extracellular membrane structures involved in many physiological and pathological processes including cancerogenesis and metastasis. The purpose of the study was to isolate, identify and analyze the total content of exosomes in biological fluids. The exosomes from the plasma and ascites samples of the patients with ovarian cancer, from the blood plasma of the patients with colorectal and head and neck squamous cell cancer as well as from the blood plasma of healthy donors were characterized using transmission electron microscopy and flow cytometry. The subpopulations of the exosomes in the biological fluids of the patients with different types of cancer were similar, but the protein concentrations of exosomes were different. In this paper we present the methodological approaches allowing us to obtain high quality exosome preparations from biological fluids.

Язык оригиналаанглийский
Название основной публикацииPHYSICS OF CANCER: INTERDISCIPLINARY PROBLEMS AND CLINICAL APPLICATIONS (PC IPCA)
Подзаголовок основной публикацииInterdisciplinary Problems and Clinical Applications - Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017
РедакторыEY Gutmanas, OB Naimark, YP Sharkeev
ИздательAmerican Institute of Physics Inc.
Число страниц4
Том1882
ISBN (электронное издание)9780735415621
DOI
СостояниеОпубликовано - 28 сен 2017
СобытиеInternational Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 - Tomsk, Российская Федерация
Продолжительность: 23 мая 201726 мая 2017

Серия публикаций

НазваниеAIP Conference Proceedings
ИздательAMER INST PHYSICS
Том1882
ISSN (печатное издание)0094-243X

Конференция

КонференцияInternational Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017
СтранаРоссийская Федерация
ГородTomsk
Период23.05.201726.05.2017

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