Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers

D. V. Reshetnikov; S. S. Patrushev; E. E. Shults

doi:10.1007/s10600-020-03169-x

Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers

D. V. Reshetnikov, S. S. Patrushev, E. E. Shults

Кафедра органической химии ФЕН

Результат исследования: Научные публикации в периодических изданиях › статья › рецензирование

Аннотация

8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.

Язык оригинала	английский
Страницы (с-по)	855-860
Число страниц	6
Журнал	Chemistry of Natural Compounds
Том	56
Номер выпуска	5
DOI	https://doi.org/10.1007/s10600-020-03169-x
Состояние	Опубликовано - 1 сен 2020

Предметные области OECD FOS+WOS

3.01.TU ФАРМАКОЛОГИЯ И ФАРМАЦИЯ

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10.1007/s10600-020-03169-x

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abstract = "8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.",

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Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers. / Reshetnikov, D. V.; Patrushev, S. S.; Shults, E. E.

В: Chemistry of Natural Compounds, Том 56, № 5, 01.09.2020, стр. 855-860.

Результат исследования: Научные публикации в периодических изданиях › статья › рецензирование

TY - JOUR

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AU - Shults, E. E.

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KW - caffeine

KW - eudesmanolides

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