@article{676180d188f145a7bf33629239054666,
title = "Synthetic Transformations of Sesquiterpene Lactones. 11.* Conjugates Based on Caffeine and Eudesmanolides with N-Containing Linkers",
abstract = "8-(Aminoalkylamino)caffeine or 8-(piperazinyl)caffeine were formed in high yields by reacting 8-bromo- or 8-chlorocaffeine with linear and cyclic diamines using microwave-assisted organic synthesis. These amines were highly reactive in Michael reactions with sesquiterpene lactones containing active methylene groups. Conjugates with caffeine and eudesmanolide moieties bonded by a N-containing linker were synthesized.",
keywords = "caffeine, eudesmanolides, methylenelactones, Michael reaction",
author = "Reshetnikov, {D. V.} and Patrushev, {S. S.} and Shults, {E. E.}",
note = "Publisher Copyright: {\textcopyright} 2020, Springer Science+Business Media, LLC, part of Springer Nature. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = sep,
day = "1",
doi = "10.1007/s10600-020-03169-x",
language = "English",
volume = "56",
pages = "855--860",
journal = "Chemistry of Natural Compounds",
issn = "0009-3130",
publisher = "Springer New York",
number = "5",
}