Аннотация
[Figure not available: see fulltext.] The cross coupling of 5'-ethynyllappaconitine with benzoic acid chlorides under the conditions of the Sonogashira reaction in benzene leads to the corresponding 5-alkynones. By condensation of the obtained 5'-alkynones with amidines, compounds with hybrid structure containing fragments of a diterpene alkaloid and pyrimidine were synthesized. The yields of the target compounds were 67–90%. The possibility of carrying out the cross coupling – condensation reaction as a one-pot synthesis is demonstrated.
Язык оригинала | английский |
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Страницы (с-по) | 1131-1138 |
Число страниц | 8 |
Журнал | Chemistry of Heterocyclic Compounds |
Том | 54 |
Номер выпуска | 12 |
DOI | |
Состояние | Опубликовано - 18 янв 2019 |