Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones

Elena Chugunova; Vladimir Samsonov; Nurgali Akylbekov; Dmitrii Mazhukin

doi:10.1016/j.tet.2017.05.078

Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones

Elena Chugunova, Vladimir Samsonov, Nurgali Akylbekov, Dmitrii Mazhukin

Лаборатория химии свободных радикалов ФЕН

Результат исследования: Научные публикации в периодических изданиях › статья

2 Цитирования (Scopus)

Аннотация

The synthesis of novel 2H-benzimidazole 1,3-dioxides on the basis of o-benzoquinone dioximes interaction with ketones in the presence of acids is described. Nitration of these compounds by nitric acid in acetic acid yields the 5-nitro derivatives of 2H-benzimidazole 1,3-dioxide.

Язык оригинала	английский
Страницы (с-по)	3986-3992
Число страниц	7
Журнал	Tetrahedron
Том	73
Номер выпуска	27-28
DOI	https://doi.org/10.1016/j.tet.2017.05.078
Состояние	Опубликовано - 6 июл 2017

Доступ к документу

10.1016/j.tet.2017.05.078

Link to publication in Scopus

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Цитировать

Chugunova, E., Samsonov, V., Akylbekov, N., & Mazhukin, D. (2017). Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones. Tetrahedron, 73(27-28), 3986-3992. https://doi.org/10.1016/j.tet.2017.05.078

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abstract = "The synthesis of novel 2H-benzimidazole 1,3-dioxides on the basis of o-benzoquinone dioximes interaction with ketones in the presence of acids is described. Nitration of these compounds by nitric acid in acetic acid yields the 5-nitro derivatives of 2H-benzimidazole 1,3-dioxide.",

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author = "Elena Chugunova and Vladimir Samsonov and Nurgali Akylbekov and Dmitrii Mazhukin",

year = "2017",

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Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones. / Chugunova, Elena; Samsonov, Vladimir; Akylbekov, Nurgali; Mazhukin, Dmitrii.

В: Tetrahedron, Том 73, № 27-28, 06.07.2017, стр. 3986-3992.

Результат исследования: Научные публикации в периодических изданиях › статья

TY - JOUR

T1 - Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones

AU - Chugunova, Elena

AU - Samsonov, Vladimir

AU - Akylbekov, Nurgali

AU - Mazhukin, Dmitrii

PY - 2017/7/6

Y1 - 2017/7/6

N2 - The synthesis of novel 2H-benzimidazole 1,3-dioxides on the basis of o-benzoquinone dioximes interaction with ketones in the presence of acids is described. Nitration of these compounds by nitric acid in acetic acid yields the 5-nitro derivatives of 2H-benzimidazole 1,3-dioxide.

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KW - 2H-benzimidazole 1,3-dioxide

KW - Ketone

KW - Nitration

KW - o-Benzoquinone dioxime

KW - Separase inhibitor

KW - DERIVATIVES

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