Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones

I. V. Il’ina; D. V. Korchagina; E. A. Morozova; T. G. Tolstikova; K. P. Volcho; N. F. Salakhutdinov

doi:10.1007/s11172-019-2520-5

Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones

I. V. Il’ina, D. V. Korchagina, E. A. Morozova, T. G. Tolstikova, K. P. Volcho, N. F. Salakhutdinov

Результат исследования: Научные публикации в периодических изданиях › статья › рецензирование

1 Цитирования (Scopus)

Аннотация

A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid (—)-isopulegol. A condensation product of (—)-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.

Язык оригинала	английский
Страницы (с-по)	1061-1066
Число страниц	6
Журнал	Russian Chemical Bulletin
Том	68
Номер выпуска	5
DOI	https://doi.org/10.1007/s11172-019-2520-5
Состояние	Опубликовано - 1 мая 2019

Доступ к документу

10.1007/s11172-019-2520-5

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Цитировать

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Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones. / Il’ina, I. V.; Korchagina, D. V.; Morozova, E. A.; Tolstikova, T. G.; Volcho, K. P.; Salakhutdinov, N. F.

В: Russian Chemical Bulletin, Том 68, № 5, 01.05.2019, стр. 1061-1066.

Результат исследования: Научные публикации в периодических изданиях › статья › рецензирование

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T1 - Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones

AU - Il’ina, I. V.

AU - Korchagina, D. V.

AU - Morozova, E. A.

AU - Tolstikova, T. G.

AU - Volcho, K. P.

AU - Salakhutdinov, N. F.

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KW - heterocyclic compounds

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