Substrate specificities of DNA glycosylases in vitro and in vivo

Антон Валентинович Ендуткин; Дмитрий Олегович Жарков

doi:10.1039/9781839160769-00175

Substrate specificities of DNA glycosylases in vitro and in vivo

Антон Валентинович Ендуткин, Дмитрий Олегович Жарков

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференций › глава (рецензируемая) › рецензирование

Аннотация

DNA glycosylases are enzymes that remove damaged bases from DNA and initiate the process of base excision repair. In vitro, many of these enzymes can excise numerous chemically similar damaged bases, yet their ability to process DNA lesions in the cellular environment is likely narrower. This chapter covers biochemical and genetic evidence for biologically relevant substrates of human and bacterial DNA glycosylases

Язык оригинала	английский
Название основной публикации	DNA Damage, DNA Repair and Disease
Подзаголовок основной публикации	Volume 1
Редакторы	Miral Dizdaroglu, R Stephen Lloyd
Место публикации	London
Издатель	Royal Society of Chemistry
Глава	8
Страницы	275-203
Число страниц	29
Том	1
ISBN (электронное издание)	978-1-83916-076-9, 978-1-83916-086-8
ISBN (печатное издание)	978-1-78801-889-0
DOI	https://doi.org/10.1039/9781839160769-00175
Состояние	Опубликовано - 2021

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10.1039/9781839160769-00175

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Substrate specificities of DNA glycosylases in vitro and in vivo. / Ендуткин, Антон Валентинович ; Жарков, Дмитрий Олегович.

DNA Damage, DNA Repair and Disease: Volume 1. ред. / Miral Dizdaroglu; R Stephen Lloyd. Том 1 London : Royal Society of Chemistry, 2021. стр. 275-203.

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференций › глава (рецензируемая) › рецензирование

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AU - Ендуткин, Антон Валентинович

AU - Жарков, Дмитрий Олегович

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N2 - DNA glycosylases are enzymes that remove damaged bases from DNA and initiate the process of base excision repair. In vitro, many of these enzymes can excise numerous chemically similar damaged bases, yet their ability to process DNA lesions in the cellular environment is likely narrower. This chapter covers biochemical and genetic evidence for biologically relevant substrates of human and bacterial DNA glycosylases

AB - DNA glycosylases are enzymes that remove damaged bases from DNA and initiate the process of base excision repair. In vitro, many of these enzymes can excise numerous chemically similar damaged bases, yet their ability to process DNA lesions in the cellular environment is likely narrower. This chapter covers biochemical and genetic evidence for biologically relevant substrates of human and bacterial DNA glycosylases

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DO - 10.1039/9781839160769-00175

M3 - Chapter (peer-reviewed)

SN - 978-1-78801-889-0

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SP - 275

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BT - DNA Damage, DNA Repair and Disease

A2 - Dizdaroglu, Miral

A2 - Lloyd, R Stephen

PB - Royal Society of Chemistry

CY - London

ER -

Substrate specificities of DNA glycosylases in vitro and in vivo

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