Аннотация
To increase the sensitivity and specificity of the developed methods for diagnosis of oncological diseases using exosomes of blood, a stage of pre-selection of tumor exosomes from a common pool of circulating microvesicles is required. In the present work, universal proteins have been identified, their expression has been increased in the exosomes of patients with colorectal cancer, head and neck squamous cell carcinomas, and lung cancer. The use of antibodies against major exosomal proteins will further develop a simple and high-performance method of affinity isolation of tumor exosomes.
Переведенное название | Sravnitel'nyĭ subpopuliatsionnyĭ analiz ékzosom plazmy krovi bol'nykh zlokachestvennymi novoobrazovaniiami |
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Язык оригинала | английский |
Страницы (с-по) | 110-114 |
Число страниц | 5 |
Журнал | Biomeditsinskaya Khimiya |
Том | 64 |
Номер выпуска | 1 |
DOI | |
Состояние | Опубликовано - 1 янв. 2018 |
Ключевые слова
- Cell-Derived Microparticles
- Exosomes
- Humans
- Lung Neoplasms
- Proteins