Reproductive potential of the male (RPM): the computer database of phenotypic and molecular genetic data for Russian men with impaired and normal fertility

Anton Bogomolov, Alexander Osadchuk, Ludmila Osadchuk

Результат исследования: Научные публикации в периодических изданияхстатьярецензирование

Аннотация

Currently, a trend of decline in male fertility is observed all over the world. The study of this trend has not only of scientific, but also of socio-economic importance. Many countries conduct studies of male reproductive potential and search environmental and genetic causes of the mentioned phenomenon. Previously published studies have not included data on the Russian male population. This work presents novel database "Reproductive Potential of the Male population of Russia" (RPM), which is almost the only source of such information about Russia. RPM was created using relational database management system MariaDB and is available at www.sysbio.ru/rpm. The database includes reproductive information of 1390 male volunteers from five large cities of Russia: Arkhangelsk, Novosibirsk, Kemerovo, Ulan-Ude and Yakutsk. The important feature of the developed database is the unique data of amultifactorial measurement of male fertility: spermatogenic, hormonal, metabolic and anthropological indices. The scientists can use published information in their studies of male reproductive potential as data of some Russian regions and compare it with data from other countries. Also the published data can be used to identify markers of infertility and subfertility, as well as to study ethnic and regional trends in fertility variability and demographic risks in Russia.

Язык оригиналаанглийский
Номер статьи20200032
Число страниц9
ЖурналJournal of integrative bioinformatics
Том17
Номер выпуска4
DOI
СостояниеОпубликовано - дек 2020

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