Precision nomenclature for the new genomics

Harris A. Lewin, Jennifer A.Marshall Graves, Oliver A. Ryder, Alexander S. Graphodatsky, Stephen J. O'Brien

Результат исследования: Научные публикации в периодических изданияхобзорная статьярецензирование

5 Цитирования (Scopus)


The confluence of two scientific disciplines may lead to nomenclature conflicts that require new terms while respecting historical definitions. This is the situation with the current state of cytology and genomics, which offer examples of distinct nomenclature and vocabularies that require reconciliation. In this article, we propose the new terms C-scaffold (for chromosome-scale assemblies of sequenced DNA fragments, commonly named scaffolds) and scaffotype (the resulting collection of C-scaffolds that represent an organism's genome). This nomenclature avoids conflict with the historical definitions of the terms chromosome (a microscopic body made of DNA and protein) and karyotype (the collection of images of all chromosomes of an organism or species). As large-scale sequencing projects progress, adoption of this nomenclature will assist end users to properly classify genome assemblies, thus facilitating genomic analysis.

Язык оригиналаанглийский
Номер статьиgiz086
Число страниц3
Номер выпуска8
СостояниеОпубликовано - 1 авг. 2019


Подробные сведения о темах исследования «Precision nomenclature for the new genomics». Вместе они формируют уникальный семантический отпечаток (fingerprint).