The article focuses on preventive lymphology as one of the most effective directions against aging. We implemented the idea of managing the workability of the mesenteric lymph node, including its functional components - structure, hydration level and trace element exchange. Phytotherapy deserves special attention in assessing the effect on the lymph node. Calculation-analytical evaluation showed that phytocorrection changes the rate and intensity of lymph node changes in natural aging. We identified basic indicators that characterize the end results of all changes in lymph node structures compared to baseline. Restoration of lymph node workability occurs with change of growth rate of intranodular functional systems. It has been shown that the growth ratio approaches the initial (basic) level due to modification of structure (compartments) and increase of water saturation of the senile lymph node after phytocorrection. The growth coefficient exceeds the base level, characterizing an increase of trace elements concentration after phytocorrection. The total growth coefficient has the greatest value compared to natural aging. Intace of phytocomposition positively affects the lymph node, slowing the involution of compartments, increasing hydration and trace element concentration. Phytotherapy prevents the onset of aging and ensures the reliability of the lymph node.