One-pot synthesis of fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes

Larisa Politanskaya, Jiaying Wang, Nadezhda Troshkova, Igor Chuikov, Irina Bagryanskaya

Результат исследования: Научные публикации в периодических изданияхстатьярецензирование

Аннотация

A facile p-toluenesulfonic acid–catalyzed one-pot synthesis of biologically interesting fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes is described. This synthetic method is metal-free, operationally simple, cheap and productive. It provides a rapid access to the title compounds as well as their 3-benzylidene and 8-cinnamoyl derivatives, that are of interest as objects for the evaluation of their pharmacological properties.

Язык оригиналаанглийский
Номер статьи110045
ЖурналJournal of Fluorine Chemistry
Том263
DOI
СостояниеОпубликовано - нояб. 2022

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  • 1.06 БИОЛОГИЧЕСКИЕ НАУКИ
  • 1.04 ХИМИЧЕСКИЕ НАУКИ

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