Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties

Irina I. Popadyuk, Oksana V. Salomatina, Nariman F. Salakhutdinov

Результат исследования: Научные публикации в периодических изданияхобзорная статья

6 Цитирования (Scopus)

Аннотация

Data published in the period from 2000 to 2015 on chemical transformations of the major human bile acids (cholic, chenodeoxycholic, deoxycholic and lithocholic acids) and ursodeoxycholic acid are integrated and described systematically. Characteristic features of their structures, biosynthesis, main sources and biological functions are considered. The data on chemical transformations of the indicated bile acids include reactions involving modifications of the side chain or the steroid nucleus. The biological activities and applications of these derivatives are surveyed in brief. The bibliography includes 227 references.

Язык оригиналаанглийский
Страницы (с-по)388-443
Число страниц56
ЖурналRussian Chemical Reviews
Том86
Номер выпуска5
DOI
СостояниеОпубликовано - 2017

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