Meet your MAKR: the membrane-associated kinase regulator protein family in the regulation of plant development

Daria D. Novikova, Anastasia L. Korosteleva, Victoria Mironova, Yvon Jaillais

Результат исследования: Научные публикации в периодических изданияхобзорная статьярецензирование

Аннотация

A small family composed of BRI1 KINASE INHIBITOR1 (BKI1) and MEMBRANE-ASSOCIATED KINASE REGULATORS (MAKRs) has recently captured the attention of plant biologists, due to their involvement in developmental processes downstream of hormones and Receptor-Like Kinases (RLK) signalling. BKI1/MAKRs are intrinsically disordered proteins (so-called unstructured proteins) and as such lack specific domains. Instead, they are defined by the presence of two conserved linear motifs involved in the interaction with lipids and proteins, respectively. Here, we first relate the discovery of the MAKR gene family. Then, we review the individual function of characterized family members and discuss their shared and specific modes of action. Finally, we explore and summarize the structural, comparative and functional genomics data available on this gene family. Together, this review aims at building a comprehensive reference about BKI1/MAKR protein function in plants.

Язык оригиналаанглийский
ЖурналFEBS Journal
Ранняя дата в режиме онлайн20 июл 2021
DOI
СостояниеОпубликовано - 20 июл 2021

Предметные области OECD FOS+WOS

  • 1.06 БИОЛОГИЧЕСКИЕ НАУКИ
  • 1.06.CQ БИОХИМИЯ И МОЛЕКУЛЯРНАЯ БИОЛОГИЯ

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