Mn-Cr-O mixed oxide (SP) and 2%Pt/SP and 2%Ru/SP samples prepared by incipient wetness impregnation of SP with RuCl3 or H2PtCl6 water solutions were tested in ethanol oxidation (ORE, 1.6%C2H5OH + 0.58%O2 in He) and water gas shift (WGSR, 1.2%CO + 1.2%H2O in He) reactions at 400 °C and 550 °C. At close ethanol conversion over all samples, 2%Ru/SP exhibited the highest selectivity towards CO and H2 and the best activity in WGSR. Analysis of isotope responses during C2H5OH + 16O2/C2H5OH + 18O2 and C2H5OH + 16(18)O2/16(18)O2 switches revealed formation of both CO and CO2 from the same intermediate – CH3CHO. At this, oxygen in CO comes from CH3CHO, while in CO2 – from the catalyst. Final CO/CO2 and H2/H2O ratios are determined by WGSR which obeys redox mechanism. It is faster reoxidation of Run+ by H2O (and probably, CO2) that is responsible for highest yield of syngas products on 2%Ru/SP sample.