We report a measurement of the branching fraction and final-state asymmetry for the B0?KS0K±p± decays. The analysis is based on a data sample of 711 fb-1 collected at the ?(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. We obtain a branching fraction of (3.60±0.33±0.15)×10-6 and a final-state asymmetry of (-8.5±8.9±0.2)%, where the first uncertainties are statistical and the second are systematic. Hints of peaking structures are found in the differential branching fractions measured as functions of Dalitz variables.