Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers

Ekaterina V. Svezhentseva; Anton A. Ivanov; Yuri A. Vorotnikov; Svetlana N. Gyrylova; Olga G. Kurskaya; Marina A. Gulyaeva; Alexander Y. Alekseev; Yuri V. Mironov; Michael A. Shestopalov; Alexander M. Shestopalov

doi:10.1016/j.matpr.2017.09.022

Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers

Ekaterina V. Svezhentseva, Anton A. Ivanov, Yuri A. Vorotnikov, Svetlana N. Gyrylova, Olga G. Kurskaya, Marina A. Gulyaeva, Alexander Y. Alekseev, Yuri V. Mironov, Michael A. Shestopalov, Alexander M. Shestopalov

Результат исследования: Научные публикации в периодических изданиях › статья

4 Цитирования (Scopus)

Аннотация

Herein we report the comparative study of cytotoxicity of a series of hexarhenium cluster complexes of general formula [{Re₆Q₈}L₆]ⁿ (Q = S, Se, Te; L = P(CH₂CH₂COO^-)₃, SO₃ ^2-, OH^-, CN^-) in the presence of hydrophilic polymers: dextran-70 (Mw ∼70 kDa) and polyethylene glycol (Mw ∼40 kDa) and their oxidised derivatives. It was demonstrated that cluster complexes in the presence of dextran polymers are generally more cytotoxic than non-coated cluster complexes, while PEG-coated cluster complexes are vice versa less cytotoxic.

Язык оригинала	английский
Страницы (с-по)	11430-11436
Число страниц	7
Журнал	Materials Today: Proceedings
Том	4
Номер выпуска	11
DOI	https://doi.org/10.1016/j.matpr.2017.09.022
Состояние	Опубликовано - 2017

Доступ к документу

10.1016/j.matpr.2017.09.022

Link to publication in Scopus

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Цитировать

Svezhentseva, E. V., Ivanov, A. A., Vorotnikov, Y. A., Gyrylova, S. N., Kurskaya, O. G., Gulyaeva, M. A., Alekseev, A. Y., Mironov, Y. V., Shestopalov, M. A., & Shestopalov, A. M. (2017). Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers. Materials Today: Proceedings, 4(11), 11430-11436. https://doi.org/10.1016/j.matpr.2017.09.022

Svezhentseva, Ekaterina V. ; Ivanov, Anton A. ; Vorotnikov, Yuri A. ; Gyrylova, Svetlana N. ; Kurskaya, Olga G. ; Gulyaeva, Marina A. ; Alekseev, Alexander Y. ; Mironov, Yuri V. ; Shestopalov, Michael A. ; Shestopalov, Alexander M. / Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers. В: Materials Today: Proceedings. 2017 ; Том 4, № 11. стр. 11430-11436.

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title = "Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers",

abstract = "Herein we report the comparative study of cytotoxicity of a series of hexarhenium cluster complexes of general formula [{Re6Q8}L6]n (Q = S, Se, Te; L = P(CH2CH2COO-)3, SO3 2-, OH-, CN-) in the presence of hydrophilic polymers: dextran-70 (Mw ∼70 kDa) and polyethylene glycol (Mw ∼40 kDa) and their oxidised derivatives. It was demonstrated that cluster complexes in the presence of dextran polymers are generally more cytotoxic than non-coated cluster complexes, while PEG-coated cluster complexes are vice versa less cytotoxic.",

keywords = "Cytotoxicity, Hydrophilic polymers, Rhenium clusters, hydrophilic polymers, ANTIBIOTICS, rhenium clusters, MOLYBDENUM, TOXICITY, cytotoxicity, RHENIUM",

author = "Svezhentseva, {Ekaterina V.} and Ivanov, {Anton A.} and Vorotnikov, {Yuri A.} and Gyrylova, {Svetlana N.} and Kurskaya, {Olga G.} and Gulyaeva, {Marina A.} and Alekseev, {Alexander Y.} and Mironov, {Yuri V.} and Shestopalov, {Michael A.} and Shestopalov, {Alexander M.}",

year = "2017",

doi = "10.1016/j.matpr.2017.09.022",

language = "English",

volume = "4",

pages = "11430--11436",

journal = "Materials Today: Proceedings",

issn = "2214-7853",

publisher = "Elsevier Science B.V.",

number = "11",

}

Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers. / Svezhentseva, Ekaterina V.; Ivanov, Anton A.; Vorotnikov, Yuri A.; Gyrylova, Svetlana N.; Kurskaya, Olga G.; Gulyaeva, Marina A.; Alekseev, Alexander Y.; Mironov, Yuri V.; Shestopalov, Michael A.; Shestopalov, Alexander M.

В: Materials Today: Proceedings, Том 4, № 11, 2017, стр. 11430-11436.

Результат исследования: Научные публикации в периодических изданиях › статья

TY - JOUR

T1 - Materials based on X-ray contrast octahedral metal cluster complexes and hydrophilic polymers

AU - Svezhentseva, Ekaterina V.

AU - Ivanov, Anton A.

AU - Vorotnikov, Yuri A.

AU - Gyrylova, Svetlana N.

AU - Kurskaya, Olga G.

AU - Gulyaeva, Marina A.

AU - Alekseev, Alexander Y.

AU - Mironov, Yuri V.

AU - Shestopalov, Michael A.

AU - Shestopalov, Alexander M.

PY - 2017

Y1 - 2017

N2 - Herein we report the comparative study of cytotoxicity of a series of hexarhenium cluster complexes of general formula [{Re6Q8}L6]n (Q = S, Se, Te; L = P(CH2CH2COO-)3, SO3 2-, OH-, CN-) in the presence of hydrophilic polymers: dextran-70 (Mw ∼70 kDa) and polyethylene glycol (Mw ∼40 kDa) and their oxidised derivatives. It was demonstrated that cluster complexes in the presence of dextran polymers are generally more cytotoxic than non-coated cluster complexes, while PEG-coated cluster complexes are vice versa less cytotoxic.

AB - Herein we report the comparative study of cytotoxicity of a series of hexarhenium cluster complexes of general formula [{Re6Q8}L6]n (Q = S, Se, Te; L = P(CH2CH2COO-)3, SO3 2-, OH-, CN-) in the presence of hydrophilic polymers: dextran-70 (Mw ∼70 kDa) and polyethylene glycol (Mw ∼40 kDa) and their oxidised derivatives. It was demonstrated that cluster complexes in the presence of dextran polymers are generally more cytotoxic than non-coated cluster complexes, while PEG-coated cluster complexes are vice versa less cytotoxic.

KW - Cytotoxicity

KW - Hydrophilic polymers

KW - Rhenium clusters

KW - hydrophilic polymers

KW - ANTIBIOTICS

KW - rhenium clusters

KW - MOLYBDENUM

KW - TOXICITY

KW - cytotoxicity

KW - RHENIUM

UR - http://www.scopus.com/inward/record.url?scp=85021777717&partnerID=8YFLogxK

U2 - 10.1016/j.matpr.2017.09.022

DO - 10.1016/j.matpr.2017.09.022

M3 - Article

AN - SCOPUS:85021777717

VL - 4

SP - 11430

EP - 11436

JO - Materials Today: Proceedings

JF - Materials Today: Proceedings

SN - 2214-7853

IS - 11

ER -