Аннотация
The research purpose is to estimate the structural organization of lymph nodes of different localization at natural (physiological) and premature aging respectively at OXYS and Wistar rats. We used a morphological method of a research. The age-induced changes of lymphoid tissue of Wistar and OXYS rats differ with type of the immune response and morphological variant of lymph nodes structure. The immune response on humoral type is formed in mesenteric and inguinal lymph nodes, and the immune response on cellular type is formed in a tracheobronchial lymph node. We noted reduction of structures of cortical substance, especially lymphoid follicles and a paracortex, and expansion of medullary substance in a lymph node of OXYS rats. Lymph nodes are subject big morphological changes at rats of OXYS, than at old rats of Wistar. Observed changes of structure of lymph nodes of OXYS rats are a morphological equivalent of premature aging and confirms early decrease of a drainage and immune function of lymph nodes
Язык оригинала | английский |
---|---|
Название основной публикации | Lymph nodes morphology as predictor natural and premature aging |
Подзаголовок основной публикации | Bioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia) |
Место публикации | Novosibirsk: ICG SB RAS |
Издатель | Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences |
Страницы | 642-643 |
Число страниц | 2 |
ISBN (печатное издание) | 978-5-91291-051-7 |
DOI | |
Состояние | Опубликовано - июл 2020 |
Событие | Bioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia) - ICG SB RAS, Новосибирск, Российская Федерация Продолжительность: 6 июл 2020 → 10 июл 2020 Номер конференции: 12 https://bgrssb.icgbio.ru/2020/ |
Конференция
Конференция | Bioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia) |
---|---|
Сокращенный заголовок | BGRS/SB-2020 |
Страна | Российская Федерация |
Город | Новосибирск |
Период | 06.07.2020 → 10.07.2020 |
Адрес в сети Интернет |