Interaction of cold atmospheric plasma jet with bio targets: Different sensitivities of human cell lines

Dm Zakrevsky, E. Yelak, P. Gugin, E. Golubitskaya, O. Troizkaja, O. Koval, S. Vagapov, I. Schweigert

Результат исследования: Научные публикации в периодических изданияхстатья по материалам конференции

Аннотация

Cold atmospheric plasma (CAP) jet device is developed and CAP jet was applied for the treatment of normal and cancer cells. The characteristics of plasma jet consisting of a sequence of cathode directed streamers are studied in the experiment and numerical fluid model simulations. A content of mixture of active radicals and ions due to plasma enhanced chemical reactions is calculated with 0D chemical model near the surface of biotarget. The evolution of spatial distribution of the streamer parameters (electric field, electron and ion density, electron energy) delivered by the streamer to the biotarget is calculated. The results of cell viability analysis of normal cells, HEK 293 (kidney embryonic stem cells) and malignant cells, A431 (skin carcinoma) demonstrate the different sensitivity to the indirect CAP jet treatment.

Язык оригиналаанглийский
Номер статьи012153
Число страниц5
ЖурналJournal of Physics: Conference Series
Том1393
Номер выпуска1
DOI
СостояниеОпубликовано - 28 ноя 2019
Событие14th International Conference on Gas Discharge Plasmas and Their Applications, GDP 2019 - Tomsk, Российская Федерация
Продолжительность: 15 сен 201921 сен 2019

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