Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13

T. V. Nikitina; A. G. Menzorov; A. A. Kashevarova; M. M. Gridina; A. A. Khabarova; Yu S. Yakovleva; M. E. Lopatkina; I. E. Pristyazhnyuk; S. A. Vasilyev; O. L. Serov; I. N. Lebedev

doi:10.1016/j.scr.2018.11.009

Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13

T. V. Nikitina, A. G. Menzorov, A. A. Kashevarova, M. M. Gridina, A. A. Khabarova, Yu S. Yakovleva, M. E. Lopatkina, I. E. Pristyazhnyuk, S. A. Vasilyev, O. L. Serov, I. N. Lebedev

Кафедра цитологии и генетики ФЕН

Результат исследования: Научные публикации в периодических изданиях › статья

2 Цитирования (Scopus)

Аннотация

Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13 were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation. IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13.

Язык оригинала	английский
Страницы (с-по)	260-264
Число страниц	5
Журнал	Stem Cell Research
Том	33
DOI	https://doi.org/10.1016/j.scr.2018.11.009
Состояние	Опубликовано - 1 дек 2018

Доступ к документу

10.1016/j.scr.2018.11.009

Link to publication in Scopus

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Цитировать

Nikitina, T. V., Menzorov, A. G., Kashevarova, A. A., Gridina, M. M., Khabarova, A. A., Yakovleva, Y. S., Lopatkina, M. E., Pristyazhnyuk, I. E., Vasilyev, S. A., Serov, O. L., & Lebedev, I. N. (2018). Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13. Stem Cell Research, 33, 260-264. https://doi.org/10.1016/j.scr.2018.11.009

Nikitina, T. V. ; Menzorov, A. G. ; Kashevarova, A. A. ; Gridina, M. M. ; Khabarova, A. A. ; Yakovleva, Yu S. ; Lopatkina, M. E. ; Pristyazhnyuk, I. E. ; Vasilyev, S. A. ; Serov, O. L. ; Lebedev, I. N. / Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13. В: Stem Cell Research. 2018 ; Том 33. стр. 260-264.

@article{51e1d839262c47b99c9f3575c615a90b,

title = "Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13",

abstract = "Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13 were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation. IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13.",

keywords = "CULTURES, Skin/metabolism, Fibroblasts/metabolism, Humans, Chromosomes, Human, Pair 13, Induced Pluripotent Stem Cells/metabolism, Male, Mentally Disabled Persons, Aged, Ring Chromosomes",

author = "Nikitina, {T. V.} and Menzorov, {A. G.} and Kashevarova, {A. A.} and Gridina, {M. M.} and Khabarova, {A. A.} and Yakovleva, {Yu S.} and Lopatkina, {M. E.} and Pristyazhnyuk, {I. E.} and Vasilyev, {S. A.} and Serov, {O. L.} and Lebedev, {I. N.}",

year = "2018",

month = dec,

day = "1",

doi = "10.1016/j.scr.2018.11.009",

language = "English",

volume = "33",

pages = "260--264",

journal = "Stem Cell Research",

issn = "1873-5061",

publisher = "Elsevier",

}

Nikitina, TV, Menzorov, AG, Kashevarova, AA, Gridina, MM, Khabarova, AA, Yakovleva, YS, Lopatkina, ME, Pristyazhnyuk, IE, Vasilyev, SA, Serov, OL & Lebedev, IN 2018, 'Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13', Stem Cell Research, том. 33, стр. 260-264. https://doi.org/10.1016/j.scr.2018.11.009

Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13. / Nikitina, T. V.; Menzorov, A. G.; Kashevarova, A. A.; Gridina, M. M.; Khabarova, A. A.; Yakovleva, Yu S.; Lopatkina, M. E.; Pristyazhnyuk, I. E.; Vasilyev, S. A.; Serov, O. L.; Lebedev, I. N.

В: Stem Cell Research, Том 33, 01.12.2018, стр. 260-264.

Результат исследования: Научные публикации в периодических изданиях › статья

TY - JOUR

T1 - Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13

AU - Nikitina, T. V.

AU - Menzorov, A. G.

AU - Kashevarova, A. A.

AU - Gridina, M. M.

AU - Khabarova, A. A.

AU - Yakovleva, Yu S.

AU - Lopatkina, M. E.

AU - Pristyazhnyuk, I. E.

AU - Vasilyev, S. A.

AU - Serov, O. L.

AU - Lebedev, I. N.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13 were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation. IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13.

AB - Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13 were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation. IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13.

KW - CULTURES

KW - Skin/metabolism

KW - Fibroblasts/metabolism

KW - Humans

KW - Chromosomes, Human, Pair 13

KW - Induced Pluripotent Stem Cells/metabolism

KW - Male

KW - Mentally Disabled Persons

KW - Aged

KW - Ring Chromosomes

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U2 - 10.1016/j.scr.2018.11.009

DO - 10.1016/j.scr.2018.11.009

M3 - Article

C2 - 30500678

AN - SCOPUS:85057271477

VL - 33

SP - 260

EP - 264

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

ER -