In silico modeling gas molecules transfer through the biomembrane by kinks-solitons

P. V. Mokrushnikov, E. V. Lezhnev, V. Ya Rudyak

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференцийстатья в сборнике материалов конференциинаучнаярецензирование

Аннотация

It is shown that the mechanism of the gas molecules transfer through the lipid bilayer can be connected with the kink-solitons. They are appeared in the lipid bilayer as a result of structural changes in biomembranes. The analytical model describing the behavior of kink-solitons in the finite hydrocarbon chain is presented. The kink-solitons are formed during the folding of the erythrocyte as it moves along the microcapillaries. The equation of the kink-soliton motion is derived. This equation is numerically solved. It is shown that kink-solitons can appear in both saturated and unsaturated alkyl chains. In unsaturated chains, the soliton is "smeared out,"CH2-groups vibrate around C=C bonds with a significant amplitude, taking away part of the soliton's energy. The transport of gas molecules by kink-solitons in unsaturated chains is hindered in comparison with saturated hydrocarbon chains. When the mechanical stress field changes, a sharp change in membrane permeability occurs.

Язык оригиналаанглийский
Название основной публикацииInternational Conference on the Methods of Aerophysical Research, ICMAR 2020
РедакторыVasily M. Fomin, Alexander Shiplyuk
ИздательAmerican Institute of Physics Inc.
ISBN (электронное издание)9780735440999
DOI
СостояниеОпубликовано - 24 мая 2021
Событие20th International Conference on the Methods of Aerophysical Research, ICMAR 2020 - Akademgorodok, Novosibirsk, Российская Федерация
Продолжительность: 1 ноя 20207 ноя 2020

Серия публикаций

НазваниеAIP Conference Proceedings
Том2351
ISSN (печатное издание)0094-243X
ISSN (электронное издание)1551-7616

Конференция

Конференция20th International Conference on the Methods of Aerophysical Research, ICMAR 2020
СтранаРоссийская Федерация
ГородAkademgorodok, Novosibirsk
Период01.11.202007.11.2020

Предметные области OECD FOS+WOS

  • 1.03 ФИЗИЧЕСКИЕ НАУКИ И АСТРОНОМИЯ

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