Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques

Kirill V. Kovtunov, Ekaterina V. Pokochueva, Oleg G. Salnikov, Samuel F. Cousin, Dennis Kurzbach, Basile Vuichoud, Sami Jannin, Eduard Y. Chekmenev, Boyd M. Goodson, Danila A. Barskiy, Igor V. Koptyug

Результат исследования: Научные публикации в периодических изданияхобзорная статья

55 Цитирования (Scopus)

Аннотация

The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.

Язык оригиналаанглийский
Страницы (с-по)1857-1871
Число страниц15
ЖурналChemistry - An Asian Journal
Том13
Номер выпуска15
Ранняя дата в режиме онлайн23 мая 2018
DOI
СостояниеОпубликовано - 6 авг 2018

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  • Цитировать

    Kovtunov, K. V., Pokochueva, E. V., Salnikov, O. G., Cousin, S. F., Kurzbach, D., Vuichoud, B., Jannin, S., Chekmenev, E. Y., Goodson, B. M., Barskiy, D. A., & Koptyug, I. V. (2018). Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques. Chemistry - An Asian Journal, 13(15), 1857-1871. https://doi.org/10.1002/asia.201800551