Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields

Sergey P. Babailov; Eugeny N. Zapolotsky; Tamara V. Basova

doi:10.1016/j.ica.2019.04.003

Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields

Sergey P. Babailov, Eugeny N. Zapolotsky, Tamara V. Basova

Результат исследования: Научные публикации в периодических изданиях › статья › рецензирование

6 Цитирования (Scopus)

Аннотация

In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by ¹H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.

Язык оригинала	английский
Страницы (с-по)	57-60
Число страниц	4
Журнал	Inorganica Chimica Acta
Том	493
DOI	https://doi.org/10.1016/j.ica.2019.04.003
Состояние	Опубликовано - 1 июл. 2019
Опубликовано для внешнего пользования	Да

Предметные области OECD FOS+WOS

1.04 ХИМИЧЕСКИЕ НАУКИ

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10.1016/j.ica.2019.04.003

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title = "Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields",

abstract = "In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.",

keywords = "Complexes of lanthanides, DOTA, Temperature sensitive NMR/MRI lanthanide paramagnetic relaxation probe, The Curie-spin contribution to the paramagnetic relaxation rate enhancements, H-1-NMR, FAST MOLECULAR-DYNAMICS, LANTHANIDES, COMPLEXES, CONFORMATIONAL DYNAMICS, NMR, RESONANCE, EUROPIUM(III), VISCOSITIES, WATER",

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Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields. / Babailov, Sergey P.; Zapolotsky, Eugeny N.; Basova, Tamara V.

В: Inorganica Chimica Acta, Том 493, 01.07.2019, стр. 57-60.

Результат исследования: Научные публикации в периодических изданиях › статья › рецензирование

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AU - Babailov, Sergey P.

AU - Zapolotsky, Eugeny N.

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KW - LANTHANIDES

KW - COMPLEXES

KW - CONFORMATIONAL DYNAMICS

KW - NMR

KW - RESONANCE

KW - EUROPIUM(III)

KW - VISCOSITIES

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