Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields

Sergey P. Babailov; Eugeny N. Zapolotsky; Tamara V. Basova

doi:10.1016/j.ica.2019.04.003

Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields

Sergey P. Babailov, Eugeny N. Zapolotsky, Tamara V. Basova

Результат исследования: Научные публикации в периодических изданиях › статья

1 Цитирования (Scopus)

Аннотация

In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by ¹H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.

Язык оригинала	английский
Страницы (с-по)	57-60
Число страниц	4
Журнал	Inorganica Chimica Acta
Том	493
DOI	https://doi.org/10.1016/j.ica.2019.04.003
Состояние	Опубликовано - 1 июл 2019
Опубликовано для внешнего пользования	Да

Доступ к документу

10.1016/j.ica.2019.04.003

Link to publication in Scopus

Fingerprint Подробные сведения о темах исследования «Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields». Вместе они формируют уникальный семантический отпечаток (fingerprint).

Цитировать

Babailov, S. P., Zapolotsky, E. N., & Basova, T. V. (2019). Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields. Inorganica Chimica Acta, 493, 57-60. https://doi.org/10.1016/j.ica.2019.04.003

@article{984f934a23d645e4a0239d35fb9f7697,

title = "Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields",

abstract = "In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.",

keywords = "Complexes of lanthanides, DOTA, Temperature sensitive NMR/MRI lanthanide paramagnetic relaxation probe, The Curie-spin contribution to the paramagnetic relaxation rate enhancements, H-1-NMR, FAST MOLECULAR-DYNAMICS, LANTHANIDES, COMPLEXES, CONFORMATIONAL DYNAMICS, NMR, RESONANCE, EUROPIUM(III), VISCOSITIES, WATER",

author = "Babailov, {Sergey P.} and Zapolotsky, {Eugeny N.} and Basova, {Tamara V.}",

year = "2019",

month = jul,

day = "1",

doi = "10.1016/j.ica.2019.04.003",

language = "English",

volume = "493",

pages = "57--60",

journal = "Inorganica Chimica Acta",

issn = "0020-1693",

publisher = "Elsevier BV",

}

Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields. / Babailov, Sergey P.; Zapolotsky, Eugeny N.; Basova, Tamara V.

В: Inorganica Chimica Acta, Том 493, 01.07.2019, стр. 57-60.

Результат исследования: Научные публикации в периодических изданиях › статья

TY - JOUR

T1 - Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields

AU - Babailov, Sergey P.

AU - Zapolotsky, Eugeny N.

AU - Basova, Tamara V.

PY - 2019/7/1

Y1 - 2019/7/1

N2 - In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.

AB - In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.

KW - Complexes of lanthanides

KW - DOTA

KW - Temperature sensitive NMR/MRI lanthanide paramagnetic relaxation probe

KW - The Curie-spin contribution to the paramagnetic relaxation rate enhancements

KW - H-1-NMR

KW - FAST MOLECULAR-DYNAMICS

KW - LANTHANIDES

KW - COMPLEXES

KW - CONFORMATIONAL DYNAMICS

KW - NMR

KW - RESONANCE

KW - EUROPIUM(III)

KW - VISCOSITIES

KW - WATER

UR - http://www.scopus.com/inward/record.url?scp=85065083520&partnerID=8YFLogxK

U2 - 10.1016/j.ica.2019.04.003

DO - 10.1016/j.ica.2019.04.003

M3 - Article

AN - SCOPUS:85065083520

VL - 493

SP - 57

EP - 60

JO - Inorganica Chimica Acta

JF - Inorganica Chimica Acta

SN - 0020-1693

ER -