High-resolution MRI data of the brain of C57BL/6J and BTBR mice in three anatomical views

Yulia A. Ryabushkina, Oleg B. Shevelev, Polina E. Kisaretova, Nikita G. Sozonov, Kseniya A. Ayriyants, Natalya P. Bondar, Vasiliy V. Reshetnikov

Результат исследования: Научные публикации в периодических изданияхстатьярецензирование


The research on strain-, sex-, and stress-specific differences in structural and functional connectivity of the brain is important for elucidating various behavioral features and etiologies of psychiatric disorders. Socially impaired BTBR mice are considered a model of autism spectrum disorders. Here we present high-resolution magnetic resonance imaging data from the brain of 89 adolescent mice (C57BL/6J and BTBR) in axial, sagittal, and coronal views. The study [1] includes both females and males differed in early-life experience (normally reared or subjected to prolonged maternal separation: 3 h daily from postnatal day 2 to 15). The MRI data were obtained on a horizontal tomograph Biospec 117/16 instrument with a magnetic field strength of 11.7 T. Thus, multislice Turbo RARE T2-weighted images of the brain were captured in eight groups of mice. Altogether, these data allow to evaluate strain-, sex-, and stress-specific alterations in the volumes of various brain structures and to better understand the relation between brain structural differences and behavioral abnormalities.

Язык оригиналаанглийский
Номер статьи107619
ЖурналData in Brief
СостояниеОпубликовано - дек 2021

Предметные области OECD FOS+WOS



Подробные сведения о темах исследования «High-resolution MRI data of the brain of C57BL/6J and BTBR mice in three anatomical views». Вместе они формируют уникальный семантический отпечаток (fingerprint).