Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis

Darya O. Prima, Elena V. Vorontsova, Arkady G. Makarov, Alexander Yu Makarov, Irina Yu Bagryanskaya, Tatiana F. Mikhailovskaya, Yuri G. Slizhov, Andrey V. Zibarev

Результат исследования: Научные публикации в периодических изданияхстатья

5 Цитирования (Scopus)

Аннотация

The title compounds synthesized from halogenated arene-1,2-diamines revealed, together with the latter, cytotoxicity towards the Hep2 (laryngeal epidermoid carcinoma) cells. The cytotoxicity was high and was accompanied by pronounced apoptotic activity at low concentrations for fluorinated diazoles, triazoles and selenadiazoles.

Язык оригиналаанглийский
Страницы (с-по)439-442
Число страниц4
ЖурналMendeleev Communications
Том27
Номер выпуска5
DOI
СостояниеОпубликовано - 1 сен 2017

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