Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population

A. A. Malakhova, E. V. Grigor'eva, S. V. Pavlova, T. B. Malankhanova, K. R. Valetdinova, Y. V. Vyatkin, E. A. Khabarova, J. A. Rzaev, S. M. Zakian, S. P. Medvedev

Результат исследования: Научные публикации в периодических изданияхстатья

Аннотация

ICGi021-A and ICGi022-A iPSC lines were obtained by reprogramming PBMCs of two healthy women of the Siberian population using episomal non-integrating vectors expressing Yamanaka factors. iPSC lines expressed pluripotency markers, had a normal karyotype and demonstrated the ability to differentiate into derivatives of the three germ layers. Clinical exome sequencing data of the original biosamples of the donors are available in the NCBI SRA database. The generated cell lines are useful as “healthy” control in biomedical studies.

Язык оригиналаанглийский
Номер статьи101952
ЖурналStem Cell Research
Том48
Ранняя дата в режиме онлайн8 авг 2020
DOI
СостояниеОпубликовано - 1 окт 2020

Fingerprint Подробные сведения о темах исследования «Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population». Вместе они формируют уникальный семантический отпечаток (fingerprint).

  • Цитировать