@article{e9222aafed0e4465bca4f113df35f676,
title = "Effects of Boron Neutron Capture Therapy on the Growth of Subcutaneous Xenografts of Human Colorectal Adenocarcinoma SW-620 in Immunodeficient Mice",
abstract = "Boron neutron capture therapy (BNCT) can become an instrument for patients with malignant neoplasms of the rectum and colon. Here we evaluate the effectiveness of BNCT performed at the accelerator based epithermal neutron source at G. I. Budker Institute of Nuclear Physics, Siberian Division of Russian Academy of Sciences, in relation to subcutaneous xenografts of human colon adenocarcinoma SW-620 in SCID mice. Utilization of BNCT with boronоphenylalanine (BPA) and sodium borocaptate (BSH), which were injected intravenously into the retroorbital sinus, resulted in a significant decrease in tumor volumes compared to the control group (no radiation).",
keywords = "accelerator based epithermal neutron source, boron neutron capture therapy, boronоphenylalanine, human colorectal adenocarcinoma, sodium borocaptate",
author = "Kanygin, {V. V.} and Kasatova, {A. I.} and Zavjalov, {E. L.} and Razumov, {I. A.} and Kolesnikov, {S. I.} and Kichigin, {A. I.} and Solov{\textquoteright}eva, {O. I.} and Tsygankova, {A. R.} and Taskaev, {S. Yu} and Kasatov, {D. A.} and Sycheva, {T. V.} and Byvaltsev, {V. A.}",
note = "The study was supported by the Russian Science Foundation (project No. 19-72-30005) using the equipment at the Common Use Center {"}Center for Genetic Resources of Laboratory Animals{"} of the Federal Research Center, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; the study was also supported by the Ministry of Education and Science of Russian Federation (Project Unique ID: RFMEFI62117X0015). Publisher Copyright: {\textcopyright} 2022, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2022",
month = jan,
doi = "10.1007/s10517-022-05392-8",
language = "English",
volume = "172",
pages = "359--363",
journal = "Bulletin of Experimental Biology and Medicine",
issn = "0007-4888",
publisher = "Springer New York",
number = "3",
}