In studies of the structure of the reaction zone in detonation waves of high explosives, it is common to measure the mechanical characteristics of the flow—the histories of particle velocity, pressure or density. Experience has shown that in such profiles, it is difficult to identify the chemical reaction zone. These distributions, as a rule, are distorted when the flow interacts with measuring systems. In this paper, we consider the prospects of an alternative electrical conductivity method, which is largely free from the above disadvantages and has a number of advantages. The correlation between the region of high electrical conductivity and the reaction zone is validated by comparing the results of conventional methods and conductivity profiles.