Deconstructing age reprogramming

Prim B. Singh, Petr P. Laktionov, Andrew G. Newman

Результат исследования: Научные публикации в периодических изданияхобзорная статьярецензирование

1 Цитирования (Scopus)

Аннотация

It has been proposed that age reprogramming enables old cells to be rejuvenated without passage through an embryonic stage (Singh and Zacouto in J Biosci 35:315–319, 2010). As such, age reprogramming stands apart from the induced pluripotent stem (iPS) and nuclear transfer-embryonic stem (NT-ES) cell therapies where histo-compatible cells are produced only after passage through an embryonic stage. It avoids many of the disadvantages associated with iPS and NT-ES cell therapies. Experimental evidence in support of age reprogramming is burgeoning. Here, we discuss possible new approaches to enhance age reprogramming, which will have considerable benefits for regenerative therapies.

Язык оригиналаанглийский
Номер статьи106
Число страниц7
ЖурналJournal of Biosciences
Том44
Номер выпуска4
DOI
СостояниеОпубликовано - 1 сен 2019

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