Аннотация
By recrystallization with different solvents as well as decomposition of betulin ethanol solvate at room temperature a new crystalline form of the biologically active compound betulin, namely hemihydrate of betulin, is obtained. By single crystal X-ray diffraction data the crystal structure of hemihydrate of betulin is determined. By powder X-ray thermodiffraction and differential scanning calorimetry it is found that when hemihydrate of betulin is heated to melting, Н2О molecules are removed and solid-phase transformations occur, which are related to the formation of an intermediate crystalline form andan orthorhombic modification of betulin.
Язык оригинала | английский |
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Страницы (с-по) | 1260-1266 |
Число страниц | 7 |
Журнал | Journal of Structural Chemistry |
Том | 61 |
Номер выпуска | 8 |
DOI | |
Состояние | Опубликовано - 1 авг 2020 |