Comparative Subpopulation Analysis of Plasma Exosomes from Cancer Patients

S. N. Tamkovich, N. V. Yunusova, A. K. Somov, S. G. Afanas’ev, G. V. Kakurina, E. S. Kolegova, E. A. Tugutova, P. P. Laktionov, I. V. Kondakova

Результат исследования: Научные публикации в периодических изданияхстатья

4 Цитирования (Scopus)

Аннотация

Pre-selection of tumor exosomes from a total pool of circulating microvesicles is an important stage required to increase sensitivity and specificity of the developing methods for diagnostics of oncological diseases. In this study, universal proteins characterized by increased expression in plasma exosomes have been identified in patients with colorectal cancer, head and neck squamous cell carcinomas, and lung cancer. The use of antibodies against major exosomal proteins will help to develop a simple and high-performance method of affinity isolation of tumor exosomes.

Язык оригиналаанглийский
Страницы (с-по)151-155
Число страниц5
ЖурналBiochemistry (Moscow) Supplement Series B: Biomedical Chemistry
Том12
Номер выпуска2
DOI
СостояниеОпубликовано - 1 апр 2018

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