TY - JOUR
T1 - Color as an important biological variable in zebrafish models
T2 - Implications for translational neurobehavioral research
AU - de Abreu, Murilo S.
AU - Giacomini, Ana C.V.V.
AU - Genario, Rafael
AU - dos Santos, Bruna E.
AU - Marcon, Leticia
AU - Demin, Konstantin A.
AU - Galstyan, David S.
AU - Strekalova, Tatiana
AU - Amstislavskaya, Tamara G.
AU - Kalueff, Allan V.
N1 - Funding Information:
ACVVG is supported by the Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (FAPERGS) research fellowships 17/2551-0001-269-0 . AVK is supported by the Southwest University (Chongqing, China) . He is the President of the International Stress and Behavior Society (ISBS, www.stress-and-behavior.com ) and the chair of the International Zebrafish Neuroscience Research Consortium (ZNRC) that coordinated this collaborative multi-laboratory project. KAD is supported by the President of Russia’s and the SPSU Rector’s Productivity Fellowships for PhD students. The laboratory is supported by the Russian Science Foundation grant 19-05-00053. TGA is supported by the budgetary funding for basic research from the Scientific Research Institute of Neurosciences and Medicine (theme AAAA-A16-116021010228-0 ).
Publisher Copyright:
© 2020 Elsevier Ltd
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/5
Y1 - 2021/5
N2 - Color is an important environmental factor that in multiple ways affects human and animal behavior and physiology. Widely used in neuroscience research, various experimental (animal) models may help improve our understanding of how different colors impact brain and behavioral processes. Complementing laboratory rodents, the zebrafish (Danio rerio) is rapidly emerging as an important novel model species to explore complex neurobehavioral processes. The growing utility of zebrafish in biomedicine makes it timely to consider the role of colors in their behavioral and physiological responses. Here, we summarize mounting evidence implicating colors as a critical variable in zebrafish models and neurobehavioral traits, with a particular relevance to CNS disease modeling, genetic and pharmacological modulation, as well as environmental enrichment and animal welfare. We also discuss the growing value of zebrafish models to study color neurobiology and color-related neurobehavioral phenomics, and outline future directions of research in this field.
AB - Color is an important environmental factor that in multiple ways affects human and animal behavior and physiology. Widely used in neuroscience research, various experimental (animal) models may help improve our understanding of how different colors impact brain and behavioral processes. Complementing laboratory rodents, the zebrafish (Danio rerio) is rapidly emerging as an important novel model species to explore complex neurobehavioral processes. The growing utility of zebrafish in biomedicine makes it timely to consider the role of colors in their behavioral and physiological responses. Here, we summarize mounting evidence implicating colors as a critical variable in zebrafish models and neurobehavioral traits, with a particular relevance to CNS disease modeling, genetic and pharmacological modulation, as well as environmental enrichment and animal welfare. We also discuss the growing value of zebrafish models to study color neurobiology and color-related neurobehavioral phenomics, and outline future directions of research in this field.
KW - Animal model
KW - Cognition
KW - Drugs
KW - Emotional behavior
KW - Social phenotypes
UR - http://www.scopus.com/inward/record.url?scp=85100121404&partnerID=8YFLogxK
U2 - 10.1016/j.neubiorev.2020.12.014
DO - 10.1016/j.neubiorev.2020.12.014
M3 - Review article
C2 - 33359096
AN - SCOPUS:85100121404
VL - 124
SP - 1
EP - 15
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
SN - 0149-7634
ER -