Biocontrol Using fMRI Signals Recorded in Real Time: A New-Generation Neurotherapy

M. E. Mel’nikov, M. B. Shtark, A. A. Savelov, A. Bruhl

    Результат исследования: Научные публикации в периодических изданияхстатьярецензирование


    This review summarizes data on the therapeutic potential of biocontrol using fMRI signals recorded in real time (rt-fMRI), a novel technology allowing patients to learn voluntary control of activity in brain areas associated with impaired functions. Positive results have now been obtained using rt-fMRI biocontrol in poststroke states, Parkinson’s disease, pain syndrome, tinnitus, alcohol and nicotine abuse, major depressive episodes, arachnophobia, and misophobia, and possibly in schizophrenia, though it is essentially ineffective in antisocial personality disorder with criminal behavior. Nonetheless, the overall significance of results is poor because of suboptimal design, the lack of control groups, or small cohort sizes. This review considers the biological mechanisms underlying the technology, its current applications and potentials, and problems related to methods and methodology.

    Язык оригиналаанглийский
    Страницы (с-по)295-316
    Число страниц22
    ЖурналNeuroscience and Behavioral Physiology
    Номер выпуска3
    СостояниеОпубликовано - 1 мар. 2018


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