Behavior and Depression Gene Networks Reconstruction and Analysis

R. A. Ivanov, V. I. Zamyatin, A. I. Klimenko, T. N. Astakhova, Y. G. Matushkin, A. N. Savostyanov, S. A. Lashin

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференцийстатья в сборнике материалов конференциинаучнаярецензирование

Аннотация

One of the main interests of modern neurophysiology is aimed at studying biology bases of anxiety and depression. The unsolved problem is complex integration between heredity factors, indexes of the brain electrical activity and psychological traits of people. Neurobiological understanding of this topic is essential not only for identification of genes involved in molecular mechanisms of depression, but also for knowledge of complex relationship of these genes. Research of these interactions could contribute to development of new prevention, diagnosis and treatment methods of depression. In our research, we reconstruct several PPI networks and networks of transcriptional regulation as well, in order to build the model of complex interaction of environmental and heredity factors of vulnerability to depression and other mental disorders. We identify the number of genes, which expression is supposedly related to environmental factors, for further experimental verification.

Язык оригиналаанглийский
Название основной публикацииSIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings
ИздательInstitute of Electrical and Electronics Engineers Inc.
Страницы361-365
Число страниц5
ISBN (электронное издание)9781728144016
DOI
СостояниеОпубликовано - окт 2019
Событие2019 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2019 - Novosibirsk, Российская Федерация
Продолжительность: 21 окт 201927 окт 2019

Серия публикаций

НазваниеSIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings

Конференция

Конференция2019 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2019
СтранаРоссийская Федерация
ГородNovosibirsk
Период21.10.201927.10.2019

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