Application of Natural Polysaccharides in Pharmaceutics

M. V. Khvostov; T. G. Tolstikova; S. A. Borisov; A. V. Dushkin

doi:10.1134/S1068162019060219

Application of Natural Polysaccharides in Pharmaceutics

M. V. Khvostov, T. G. Tolstikova, S. A. Borisov, A. V. Dushkin

Кафедра фундаментальной медицины ИМПЗ

Результат исследования: Научные публикации в периодических изданиях › обзорная статья

Аннотация

Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.

Язык оригинала	английский
Страницы (с-по)	438-450
Число страниц	13
Журнал	Russian Journal of Bioorganic Chemistry
Том	45
Номер выпуска	6
DOI	https://doi.org/10.1134/S1068162019060219
Состояние	Опубликовано - 1 ноя 2019

Доступ к документу

10.1134/S1068162019060219

Link to publication in Scopus

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Цитировать

Khvostov, M. V., Tolstikova, T. G., Borisov, S. A., & Dushkin, A. V. (2019). Application of Natural Polysaccharides in Pharmaceutics. Russian Journal of Bioorganic Chemistry, 45(6), 438-450. https://doi.org/10.1134/S1068162019060219

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title = "Application of Natural Polysaccharides in Pharmaceutics",

abstract = "Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.",

keywords = "alginates, arabinogalactan, chitosan, dextrans, hyaluronic acid, increased bioavailability, pectin, polysaccharides, pullulan",

author = "Khvostov, {M. V.} and Tolstikova, {T. G.} and Borisov, {S. A.} and Dushkin, {A. V.}",

year = "2019",

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Application of Natural Polysaccharides in Pharmaceutics. / Khvostov, M. V.; Tolstikova, T. G.; Borisov, S. A.; Dushkin, A. V.

В: Russian Journal of Bioorganic Chemistry, Том 45, № 6, 01.11.2019, стр. 438-450.

Результат исследования: Научные публикации в периодических изданиях › обзорная статья

TY - JOUR

T1 - Application of Natural Polysaccharides in Pharmaceutics

AU - Khvostov, M. V.

AU - Tolstikova, T. G.

AU - Borisov, S. A.

AU - Dushkin, A. V.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.

AB - Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.

KW - alginates

KW - arabinogalactan

KW - chitosan

KW - dextrans

KW - hyaluronic acid

KW - increased bioavailability

KW - pectin

KW - polysaccharides

KW - pullulan

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DO - 10.1134/S1068162019060219

M3 - Review article

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VL - 45

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EP - 450

JO - Russian Journal of Bioorganic Chemistry

JF - Russian Journal of Bioorganic Chemistry

SN - 1068-1620

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