Antiulcerogenic activity of borneol derivatives

M. S. Borisova; O. I. Yarovaya; M. D. Semenova; T. G. Tolstikova; N. F. Salakhutdinov

doi:10.1007/s11172-018-2110-y

Antiulcerogenic activity of borneol derivatives

M. S. Borisova, O. I. Yarovaya, M. D. Semenova, T. G. Tolstikova, N. F. Salakhutdinov

Кафедра фундаментальной медицины ИМП

Результат исследования: Научные публикации в периодических изданиях › статья

2 Цитирования (Scopus)

Аннотация

Antiulcerogenic activity of borneol and its N-heterocyclic esters was investigated using indomethacin-induced gastric ulcer model. A considerable antiulcerogenic effect comparable to that shown by Omeprazole and Famotidine was found for two investigated compounds in the indomethacin-induced gastric ulcer model. Bornyl 2-piperazinoacetate, with a non-substituted piperazine moiety, showed maximum antiulcerogenic activity in the indomethacininduced gastric ulcer model and demonstrated a significant gastroprotective effect in the ethanol-induced gastric ulcer model comparable to the effect of Omeprazole.

Язык оригинала	английский
Страницы (с-по)	558-561
Число страниц	4
Журнал	Russian Chemical Bulletin
Том	67
Номер выпуска	3
DOI	https://doi.org/10.1007/s11172-018-2110-y
Состояние	Опубликовано - 1 мар 2018

Доступ к документу

10.1007/s11172-018-2110-y

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AU - Semenova, M. D.

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AU - Salakhutdinov, N. F.

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