Аннотация
Antiulcerogenic activity of borneol and its N-heterocyclic esters was investigated using indomethacin-induced gastric ulcer model. A considerable antiulcerogenic effect comparable to that shown by Omeprazole and Famotidine was found for two investigated compounds in the indomethacin-induced gastric ulcer model. Bornyl 2-piperazinoacetate, with a non-substituted piperazine moiety, showed maximum antiulcerogenic activity in the indomethacininduced gastric ulcer model and demonstrated a significant gastroprotective effect in the ethanol-induced gastric ulcer model comparable to the effect of Omeprazole.
Язык оригинала | английский |
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Страницы (с-по) | 558-561 |
Число страниц | 4 |
Журнал | Russian Chemical Bulletin |
Том | 67 |
Номер выпуска | 3 |
DOI | |
Состояние | Опубликовано - 1 мар 2018 |