Analysis of grounded substrate effects on cold atmospheric plasma jet irradiation of cellular and animal models

I. Schweigert, A. Alexandrov, D. Zakrevsky, P. Gugin, E. Milakhina, E. Golubitskaya, O. Troitskaya, M. Biryukov, O. Koval

Результат исследования: Научные публикации в периодических изданияхстатья по материалам конференциирецензирование

Аннотация

Plasma devices with cylindrical and plane geometries generating the nonthermal atmospheric plasma jets are used for the treatment of the cancer cells in vitro and in vivo. It is shown in the simulations and experiment that the grounded substrate placed under the bio target essentially increases the plasma treatment efficiency. Nevertheless the temperature control is needed to avoid the burns in a spot of contact of plasma jet with the mice skin. The measured and calculated local temperature increase with different regimes of plasma device operation is presented. The MTT and iCELLigence assays of the viability of cancer cells in vitro show the efficiency of plasma jet treatment and mice models in vivo demonstrate the safety regime for cold atmospheric pressure plasma irradiation.

Язык оригиналаанглийский
Номер статьи012010
ЖурналJournal of Physics: Conference Series
Том1698
Номер выпуска1
DOI
СостояниеОпубликовано - 31 дек 2020
Событие19th International Workshop on Magneto-Plasma Aerodynamics, WSMPA 2020 - Moscow, Российская Федерация
Продолжительность: 15 сен 202017 сен 2020

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