Amorphous drugs: Benefits and challenges

Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch

Результат исследования: Книги, отчёты, сборникикнига, в т.ч. монография, учебникнаучнаярецензирование

19 Цитирования (Scopus)

Аннотация

This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

Язык оригиналаанглийский
ИздательSpringer International Publishing AG
Число страниц230
ISBN (электронное издание)9783319720029
ISBN (печатное издание)9783319720012
DOI
СостояниеОпубликовано - 1 янв 2018
Опубликовано для внешнего пользованияДа

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  • Цитировать

    Rams-Baron, M., Jachowicz, R., Boldyreva, E., Zhou, D., Jamroz, W., & Paluch, M. (2018). Amorphous drugs: Benefits and challenges. Springer International Publishing AG. https://doi.org/10.1007/978-3-319-72002-9