Air flow and precipitation of medicine aerosol droplets in the human bronchial tree

A. E. Medvedev, P. S. Gafurova

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференцийстатья в сборнике материалов конференциинаучнаярецензирование

Аннотация

The work is devoted to the calculation of gas flow and modeling of droplet sedimentation of medicinal aerosols in human lungs. To solve this problem, a previously constructed three-dimensional model of a human bronchial tree was used. For calculation of gas flow in lungs and aerosol deposition the method of step-by-step calculation of the flow in bronchial tree was used. It allowed to calculate the air flow and aerosol droplets deposition in all bronchial branches up to alveolus. Human breathing was calculated using COVID-19 thermal helium-oxygen mixture treatment method. Breathing with a thermal helium-oxygen mixture requires less effort from the patient than breathing with air. Three-dimensional numerical calculations of air flow and aerosol droplets in human lungs have been performed. The characteristics of a serial medical nebulizer were used to calculate the deposition of aerosol droplets. It is shown that the number of past droplets depends (except for flow, droplet size) on the duration of breath. The nebulizer under consideration does not provide delivery of medicines to the lung alveolus.

Язык оригиналаанглийский
Название основной публикацииInternational Conference on the Methods of Aerophysical Research, ICMAR 2020
РедакторыVasily M. Fomin, Alexander Shiplyuk
ИздательAmerican Institute of Physics Inc.
ISBN (электронное издание)9780735440999
DOI
СостояниеОпубликовано - 24 мая 2021
Событие20th International Conference on the Methods of Aerophysical Research, ICMAR 2020 - Akademgorodok, Novosibirsk, Российская Федерация
Продолжительность: 1 ноя 20207 ноя 2020

Серия публикаций

НазваниеAIP Conference Proceedings
Том2351
ISSN (печатное издание)0094-243X
ISSN (электронное издание)1551-7616

Конференция

Конференция20th International Conference on the Methods of Aerophysical Research, ICMAR 2020
СтранаРоссийская Федерация
ГородAkademgorodok, Novosibirsk
Период01.11.202007.11.2020

Предметные области OECD FOS+WOS

  • 1.03 ФИЗИЧЕСКИЕ НАУКИ И АСТРОНОМИЯ

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