Accelerator-based boron neutron capture therapy: in vivo experiments

Владимир Владимирович Каныгин; Анна Исмагиловна Касатова; Александр Иванович Кичигин; Евгений Леонидович Завьялов; Иван Алексеевич Разумов; Ринат Авхадиевич Мухамадияров; Сергей Юрьевич Таскаев

Accelerator-based boron neutron capture therapy: in vivo experiments

Владимир Владимирович Каныгин, Анна Исмагиловна Касатова, Александр Иванович Кичигин, Евгений Леонидович Завьялов, Иван Алексеевич Разумов, Ринат Авхадиевич Мухамадияров, Сергей Юрьевич Таскаев

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › рецензирование

Аннотация

The report is about an assessment of a beam at an accelerator neutron source at Budker Institute of Nuclear Physics and its possible application on glioblastoma tumor. An evaluation of the efficacy of boron neutron capture therapy on heterotopic glioblastoma U87 MG in SCID mice using different boron containing drugs was carried out. Accumulation of 10B in tumor and normal tissues was detected using atomic emission spectrometer ICPE-9820 (Shimadzu, Japan). Tumor growth was significantly slower in all irradiated groups from the 7th day after BNCT compared to untreated control group. The differences between experimental groups became significant from the 50th day after BNCT. Liposomal BSH showed better long-term results compared to BPA and non-liposomal BSH.

Язык оригинала	английский
Название основной публикации	19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts
Место публикации	Вена
Издатель	International Atomic Energy Agency
Страницы	152
Число страниц	1
Состояние	Опубликовано - 2021
Событие	19th International Congress on Neutron Capture Therapy - Вена, Австрия Продолжительность: 27 сент. 2021 → 1 окт. 2021 Номер конференции: 19 http://www.icnct19.org/

Конференция

Конференция	19th International Congress on Neutron Capture Therapy
Сокращенный заголовок	ICNCT
Страна/Tерритория	Австрия
Город	Вена
Период	27.09.2021 → 01.10.2021
Адрес в сети Интернет	http://www.icnct19.org/

Предметные области OECD FOS+WOS

2.02.IQ ИНЖЕНЕРИЯ, ЭЛЕКТРИЧЕСКАЯ И ЭЛЕКТРОННАЯ

ГРНТИ

47.31 Ускорители заряженных частиц и плазмы

Доступ к документу

http://irbiscorp.spsl.nsc.ru/fulltext/WORKS/2021/ICNCT.pdf

Другие файлы и ссылки

https://www.elibrary.ru/item.asp?id=48013078&pff=1

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Каныгин, В. В., Касатова, А. И., Кичигин, А. И., Завьялов, Е. Л., Разумов, И. А., Мухамадияров, Р. А., & Таскаев, С. Ю. (2021). Accelerator-based boron neutron capture therapy: in vivo experiments. В 19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts (стр. 152). [О14] International Atomic Energy Agency. http://irbiscorp.spsl.nsc.ru/fulltext/WORKS/2021/ICNCT.pdf

Каныгин, Владимир Владимирович ; Касатова, Анна Исмагиловна ; Кичигин, Александр Иванович и др. / Accelerator-based boron neutron capture therapy: in vivo experiments. 19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts. Вена : International Atomic Energy Agency, 2021. стр. 152

@inproceedings{631cac21548a4f55812269ac67905be2,

title = "Accelerator-based boron neutron capture therapy: in vivo experiments",

abstract = "The report is about an assessment of a beam at an accelerator neutron source at Budker Institute of Nuclear Physics and its possible application on glioblastoma tumor. An evaluation of the efficacy of boron neutron capture therapy on heterotopic glioblastoma U87 MG in SCID mice using different boron containing drugs was carried out. Accumulation of 10B in tumor and normal tissues was detected using atomic emission spectrometer ICPE-9820 (Shimadzu, Japan). Tumor growth was significantly slower in all irradiated groups from the 7th day after BNCT compared to untreated control group. The differences between experimental groups became significant from the 50th day after BNCT. Liposomal BSH showed better long-term results compared to BPA and non-liposomal BSH.",

author = "Каныгин, {Владимир Владимирович} and Касатова, {Анна Исмагиловна} and Кичигин, {Александр Иванович} and Завьялов, {Евгений Леонидович} and Разумов, {Иван Алексеевич} and Мухамадияров, {Ринат Авхадиевич} and Таскаев, {Сергей Юрьевич}",

year = "2021",

language = "English",

pages = "152",

booktitle = "19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts",

publisher = "International Atomic Energy Agency",

address = "Austria",

note = "19th International Congress on Neutron Capture Therapy, ICNCT ; Conference date: 27-09-2021 Through 01-10-2021",

url = "http://www.icnct19.org/",

}

Каныгин, ВВ , Касатова, АИ, Кичигин, АИ, Завьялов, ЕЛ, Разумов, ИА, Мухамадияров, РА & Таскаев, СЮ 2021, Accelerator-based boron neutron capture therapy: in vivo experiments. в 19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts., О14, International Atomic Energy Agency, Вена, стр. 152, 19th International Congress on Neutron Capture Therapy, Вена, Австрия, 27.09.2021. <http://irbiscorp.spsl.nsc.ru/fulltext/WORKS/2021/ICNCT.pdf>

Accelerator-based boron neutron capture therapy: in vivo experiments. / Каныгин, Владимир Владимирович ; Касатова, Анна Исмагиловна; Кичигин, Александр Иванович и др.

19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts. Вена : International Atomic Energy Agency, 2021. стр. 152 О14.

Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › рецензирование

TY - GEN

T1 - Accelerator-based boron neutron capture therapy: in vivo experiments

AU - Каныгин, Владимир Владимирович

AU - Касатова, Анна Исмагиловна

AU - Кичигин, Александр Иванович

AU - Завьялов, Евгений Леонидович

AU - Разумов, Иван Алексеевич

AU - Мухамадияров, Ринат Авхадиевич

AU - Таскаев, Сергей Юрьевич

N1 - Conference code: 19

PY - 2021

Y1 - 2021

N2 - The report is about an assessment of a beam at an accelerator neutron source at Budker Institute of Nuclear Physics and its possible application on glioblastoma tumor. An evaluation of the efficacy of boron neutron capture therapy on heterotopic glioblastoma U87 MG in SCID mice using different boron containing drugs was carried out. Accumulation of 10B in tumor and normal tissues was detected using atomic emission spectrometer ICPE-9820 (Shimadzu, Japan). Tumor growth was significantly slower in all irradiated groups from the 7th day after BNCT compared to untreated control group. The differences between experimental groups became significant from the 50th day after BNCT. Liposomal BSH showed better long-term results compared to BPA and non-liposomal BSH.

AB - The report is about an assessment of a beam at an accelerator neutron source at Budker Institute of Nuclear Physics and its possible application on glioblastoma tumor. An evaluation of the efficacy of boron neutron capture therapy on heterotopic glioblastoma U87 MG in SCID mice using different boron containing drugs was carried out. Accumulation of 10B in tumor and normal tissues was detected using atomic emission spectrometer ICPE-9820 (Shimadzu, Japan). Tumor growth was significantly slower in all irradiated groups from the 7th day after BNCT compared to untreated control group. The differences between experimental groups became significant from the 50th day after BNCT. Liposomal BSH showed better long-term results compared to BPA and non-liposomal BSH.

UR - https://www.elibrary.ru/item.asp?id=48013078&pff=1

M3 - Conference contribution

SP - 152

BT - 19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts

PB - International Atomic Energy Agency

CY - Вена

T2 - 19th International Congress on Neutron Capture Therapy

Y2 - 27 September 2021 through 1 October 2021

ER -

Каныгин ВВ , Касатова АИ, Кичигин АИ, Завьялов ЕЛ, Разумов ИА, Мухамадияров РА и др. Accelerator-based boron neutron capture therapy: in vivo experiments. В 19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts. Вена: International Atomic Energy Agency. 2021. стр. 152. О14

Accelerator-based boron neutron capture therapy: in vivo experiments

Аннотация

Конференция

Предметные области OECD FOS+WOS

ГРНТИ

Доступ к документу

Другие файлы и ссылки

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