Аннотация
In this paper, a problem of specifying HIV-infection parameters and immune response using additional measurements of the concentrations of the T-lymphocytes, the free virus, and the immune effectors at fixed times for a mathematical model of HIV dynamics is investigated numerically. The problem of specifying the parameters of the mathematical model (an inverse problem) is reduced to a problem of minimizing an objective function describing the deviation of the simulation results from the experimental data. A genetic algorithm for solving the least squares function minimization problem method is implemented and investigated. The results of a numerical solution of the inverse problem are analyzed.
Язык оригинала | английский |
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Название основной публикации | Proceedings - 2017 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2017 |
Издатель | Institute of Electrical and Electronics Engineers Inc. |
Страницы | 82-86 |
Число страниц | 5 |
ISBN (электронное издание) | 9781538615966 |
DOI | |
Состояние | Опубликовано - 14 ноя 2017 |
Событие | 2017 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2017 - Novosibirsk, Российская Федерация Продолжительность: 18 сен 2017 → 22 сен 2017 |
Конференция
Конференция | 2017 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2017 |
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Страна | Российская Федерация |
Город | Novosibirsk |
Период | 18.09.2017 → 22.09.2017 |