A new structure of a serotonin salt: Comparison and conformational analysis of all known serotonin complexes

Denis Rychkov, Elena V. Boldyreva, Nikolay A. Tumanov

Результат исследования: Научные публикации в периодических изданияхстатьярецензирование

7 Цитирования (Scopus)

Аннотация

Four serotonin salt structures (serotonin adipate, C10H 13N2O+·C6H9O 4 -, is a previously unknown structure) were analysed to understand the influence of the anion on serotonin conformation. Hydrogen bonding alone favours a flat conformation, whereas additional stacking interactions between ions may possibly account for the nonplanar conformation. Since molecular conformation, stability and biological activity are interrelated, one can consider influencing the chemical and biological properties of serotonin by selecting an appropriate counter-ion for salt formation.

Язык оригиналаанглийский
Страницы (с-по)1055-1061
Число страниц7
ЖурналActa Crystallographica Section C: Crystal Structure Communications
Том69
Номер выпуска9
DOI
СостояниеОпубликовано - сен 2013

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