Аннотация
Four serotonin salt structures (serotonin adipate, C10H 13N2O+·C6H9O 4 -, is a previously unknown structure) were analysed to understand the influence of the anion on serotonin conformation. Hydrogen bonding alone favours a flat conformation, whereas additional stacking interactions between ions may possibly account for the nonplanar conformation. Since molecular conformation, stability and biological activity are interrelated, one can consider influencing the chemical and biological properties of serotonin by selecting an appropriate counter-ion for salt formation.
Язык оригинала | английский |
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Страницы (с-по) | 1055-1061 |
Число страниц | 7 |
Журнал | Acta Crystallographica Section C: Crystal Structure Communications |
Том | 69 |
Номер выпуска | 9 |
DOI | |
Состояние | Опубликовано - сен 2013 |