A simple approach for isolation of exosomes from the blood plasma, which allows to obtain highly purified preparations of microvesicles no larger than 100 nm has been proposed. The presence of different subpopulations of exosomes in the blood plasma of healthy donors and cancer patients has been recognized. We found the presence of the universal markers CD9, CD24 and CD81 on exosomes isolated from blood plasma that can be used to their routine typing.
|Translated title of the contribution||Vydelenie i kharakterizatsiia ékzosom plazmy krovi bol'nykh rakom molochnoĭ zhelezy i kolorektal'nym rakom|
|Number of pages||5|
|Publication status||Published - Mar 2017|
- Breast cancer
- Colorectal cancer
- Flow cytometry
- Transmission electron microscopy