Two-phase filtration as a numerical model of embolization of arteriovenous malformation

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Abstract

Cerebral arteriovenous malformation is a congenital pathology of development, in which the arterial and venous blood channels are connected by a nidus of randomly interwoven degenerate vessels. This is a dangerous disease that affects brain functioning and the risk of intracerebral hemorrhage is high. One of AVM treatment methods is embolization - the endovascular filling of the AVM vessel bundle with a special embolic agent. This method is widely used, but still in some cases is accompanied by intraoperative rupture of AVM vessels. In this paper, the optimal scenario of AVM embolization is studied from the point of view of safety and effectiveness of the procedure. The joint movement of blood and embolic agent in the AVM body is modeled on the basis of a one-dimensional two-phase filtration model. In numerical analysis, the modification of the CABARET scheme is used. On the basis of clinical data, models for three real patients are constructed. For a special law of embolic agent delivery, acceptable and optimal scenarios of embolization are calculated.

Original languageEnglish
Title of host publication19th International Conference on the Methods of Aerophysical Research, ICMAR 2018
Editors Fomin
PublisherAmerican Institute of Physics Inc.
Number of pages9
Volume2027
ISBN (Electronic)9780735417472
DOIs
Publication statusPublished - 2 Nov 2018
Event19th International Conference on the Methods of Aerophysical Research, ICMAR 2018 - Akademgorodok, Novosibirsk, Russian Federation
Duration: 13 Aug 201819 Aug 2018

Publication series

NameAIP Conference Proceedings
PublisherAMER INST PHYSICS
Volume2027
ISSN (Print)0094-243X

Conference

Conference19th International Conference on the Methods of Aerophysical Research, ICMAR 2018
Country/TerritoryRussian Federation
CityAkademgorodok, Novosibirsk
Period13.08.201819.08.2018

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