The impact of posture on the cardiac depolarization and repolarization phases of the QT interval in healthy subjects

Yurie Obata, Pavel Ruzankin, Qi Jia Ong, Dan E. Berkowitz, Ronald D. Berger, Jochen Steppan, Viachaslau Barodka

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Background Postural changes affect both heart rate and the QT interval. Objective To investigate the effects of postural changes on the depolarization and repolarization phases of the QT interval. Methods A three lead ECG from 12 healthy young volunteers was recorded in the standing, sitting and in the supine positions. For the purpose of this study, we defined the depolarization phase as the QRS complex plus the ST segment and the repolarization phase as the duration of the T wave. Results QTc did not change with changes in position. The ratio of the duration of the depolarization phase to the repolarization phase was higher in the supine position (0.98 ± 0.13) compared to the standing position (0.83 ± 0.17). Conclusions The origin of the T wave moves closer to the QRS complex during standing compared to the supine position. The observed changes are mainly due to shortening of the ST segment during standing compared to supine position.

Original languageEnglish
Pages (from-to)640-645
Number of pages6
JournalJournal of Electrocardiology
Volume50
Issue number5
DOIs
Publication statusPublished - 1 Sep 2017

Keywords

  • Depolarization
  • Electrocardiogram
  • QT interval
  • Repolarization
  • T wave
  • STIMULATION
  • HUMANS
  • EXERCISE
  • ACTION-POTENTIAL DURATION
  • DISEASE
  • RESTITUTION
  • HEART-RATE
  • ASSOCIATION
  • Humans
  • Middle Aged
  • Male
  • Posture/physiology
  • Healthy Volunteers
  • Electrocardiography
  • Adult
  • Female
  • Heart Conduction System/physiology

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