Abstract
The conditions for oxidizing methyl isopimarate to the 15-oxo-15,16-dihydroisopimarate were studied. The latter was used for one-pot syntheses of 13-(oxazol-5-yl)-15,16-bisnorisopimarates that included formation of the 16-oxoaldehyde isopimarate and its condensation with α-amino acids. The structures of the synthesized compounds were confirmed by IR, UV, and NMR spectral data and an XSA.
Original language | English |
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Pages (from-to) | 293-300 |
Number of pages | 8 |
Journal | Chemistry of Natural Compounds |
Volume | 54 |
Issue number | 2 |
DOIs | |
Publication status | Accepted/In press - 14 Apr 2018 |
Keywords
- amino acids
- isopimaric acid
- Kornblum oxidation
- oxazoles
- Wacker oxidation
- XSA
- OXIDATION
- NATURAL-PRODUCTS
- STRATEGY
- CRYSTAL-STRUCTURES
- DITERPENOIDS
- ISOPIMARIC ACID
- DERIVATIVES
- EFFICIENT